MAPRE2

Protein-coding gene in the species Homo sapiens From Wikipedia, the free encyclopedia

Microtubule-associated protein RP/EB family member 2 is a protein that in humans is encoded by the MAPRE2 gene.[5][6][7]

AliasesMAPRE2, EB1, EB2, RP1, CSCSC2, microtubule associated protein RP/EB family member 2
End35,143,470 bp[1]
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MAPRE2
Identifiers
AliasesMAPRE2, EB1, EB2, RP1, CSCSC2, microtubule associated protein RP/EB family member 2
External IDsOMIM: 605789; MGI: 106271; HomoloGene: 75027; GeneCards: MAPRE2; OMA:MAPRE2 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001143826
NM_001143827
NM_001256420
NM_014268

NM_001162941
NM_001162942
NM_153058

RefSeq (protein)

NP_001137298
NP_001137299
NP_001243349
NP_055083

NP_001156413
NP_001156414
NP_694698

Location (UCSC)Chr 18: 34.98 – 35.14 MbChr 18: 23.89 – 24.03 Mb
PubMed search[3][4]
Wikidata
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Function

The protein encoded by this gene shares significant homology to the adenomatous polyposis coli (APC) protein-binding EB1 gene family. The function of this protein is unknown; however, its homology suggests involvement in tumorigenesis of colorectal cancers and proliferative control of normal cells. This gene may belong to the intermediate/early gene family, involved in the signal transduction cascade downstream of the TCR.[7]

Interactions

MAPRE2 has been shown to interact with APC.[8][9]

References

Further reading

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