MARCKSL1

Protein-coding gene in the species Homo sapiens From Wikipedia, the free encyclopedia

MARCKS-related protein is a protein that in humans is encoded by the MARCKSL1 gene.[5][6]

AliasesMARCKSL1, F52, MACMARCKS, MLP, MLP1, MRP, MARCKS-like 1, MARCKS like 1
End32,336,233 bp[1]
Quick facts Identifiers, Aliases ...
MARCKSL1
Identifiers
AliasesMARCKSL1, F52, MACMARCKS, MLP, MLP1, MRP, MARCKS-like 1, MARCKS like 1
External IDsOMIM: 602940; MGI: 97143; HomoloGene: 40748; GeneCards: MARCKSL1; OMA:MARCKSL1 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_023009

NM_010807

RefSeq (protein)

NP_075385

NP_034937

Location (UCSC)Chr 1: 32.33 – 32.34 MbChr 4: 129.41 – 129.41 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse
Close

Function

This gene encodes a member of the myristoylated alanine-rich C-kinase substrate (MARCKS) family. MARCKS plays a role in cytoskeletal regulation, protein kinase C signaling and calmodulin signaling. The encoded protein affects the formation of adherens junctions. Alternative splicing results in multiple transcript variants.[6]

Interactions

MARCKSL1 has been shown to interact with DCTN2[7] and JNK.[8]

References

Further reading

Related Articles

Wikiwand AI