MAST2

MAST2
Identifiers
Aliases	MAST2, MAST205, MTSSK, microtubule associated serine/threonine kinase 2
External IDs	OMIM: 612257; MGI: 894676; GeneCards: MAST2
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2KQF, 2KYL
Enzyme activity
Gene location (Human)
Chr.	Chromosome 1 (human)
End	46,036,122 bp
Gene location (Mouse)
Chr.	Chromosome 4 (mouse)
End	116,464,183 bp
RNA expression pattern
	Top expressed in
	gastrocnemius muscle; ; muscle of thigh; ; apex of heart; ; gastric mucosa; ; glutes; ; stromal cell of endometrium; ; pancreatic ductal cell; ; skeletal muscle tissue; ; left ventricle; ; left testis;
	Top expressed in
	neural layer of retina; ; muscle of thigh; ; internal carotid artery; ; right ventricle; ; ankle joint; ; cardiac muscle tissue of left ventricle; ; external carotid artery; ; ankle; ; digastric muscle; ; soleus muscle;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	transferase activity; nucleotide binding; protein kinase activity; phosphatase binding; microtubule binding; metal ion binding; kinase activity; protein serine/threonine kinase activity; protein binding; ATP binding; magnesium ion binding;
Cellular component	membrane; microtubule cytoskeleton; plasma membrane; cytoskeleton; cytoplasm;
Biological process	intracellular signal transduction; phosphorylation; spermatid differentiation; protein phosphorylation; cytoskeleton organization; peptidyl-serine phosphorylation;
	Sources:Amigo / QuickGO
Orthologs
Databases	NCBI: entry; OMA: entry
	23139
	17776
	ENSG00000086015
	ENSMUSG00000003810
	Q6P0Q8
	Q60592
	NM_015112; NM_001319245; NM_001324320; NM_001324321
	NM_001042743; NM_008641; NM_001369061; NM_001369062
	NP_001306174; NP_001311249; NP_001311250; NP_055927
	NP_001036208; NP_032667; NP_001355990; NP_001355991
	Wikidata
View/Edit Human	View/Edit Mouse

Microtubule-associated serine/threonine-protein kinase 2 is an enzyme that in humans is encoded by the MAST2 gene.^[5] The protein encoded by this gene controls TRAF6 and NF-kappaB activity.^[6]