MDMB-FUBINACA
Chemical compound
From Wikipedia, the free encyclopedia
MDMB-FUBINACA (also known as MDMB(N)-Bz-F and FUB-MDMB) is an indazole-based synthetic cannabinoid that is a potent agonist for cannabinoid receptors and that has been sold online as a designer drug.[1][2] The structure of MDMB-FUBINACA contains the amino acid 3-methylvaline[citation needed], also known as l-tert-leucine.[3] MDMB-FUBINACA has Ki values of 1.14nM at CB1 and 0.1228nM at CB2 and EC50 values of 0.2668nM at CB1 and 0.1411nM at CB2.[4]
- CA: Schedule II
- DE: NpSG (Industrial and scientific use only)
- UK: Class B
- US: Schedule I
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| Formula | C22H24FN3O3 |
| Molar mass | 397.450 g·mol−1 |
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Side effects
There have been a large number of reported cases of deaths and hospitalizations in relation to this synthetic cannabinoid, mainly in Russia and Belarus. MDMB-FUBINACA was first reported in 2014 and quickly gained a reputation as the most deadly synthetic cannabinoid drug sold by 2015.[5] Up to 700 hospitalisations and 25 deaths were initially linked to MDMB-FUBINACA in media and government reports, and subsequent testing confirmed that at least 1000 hospitalisations and 40 deaths had occurred as a consequence of intoxication by MDMB-FUBINACA as of March 2015.[6][7]
Legal status
In the United States, MDMB-FUBINACA is a Schedule I controlled substance.[8]
As of October 2015, MDMB-FUBINACA is a controlled substance in Belarus, Russia,[9] and China.[10]
In July 2021, it was included in Table II-A in the list of prohibited drugs of Portugal.[citation needed]