MED30

Mediator of RNA polymerase II transcription subunit 30 is an enzyme that in humans is encoded by the MED30 gene.^[5] It represents subunit Med30 of the Mediator complex and is metazoan-specific,^[6] having no homologues in yeasts.

AliasesMED30, MED30S, THRAP6, TRAP25, mediator complex subunit 30

External IDsOMIM: 610237; MGI: 1917040; HomoloGene: 12329; GeneCards: MED30; OMA:MED30 - orthologs

Chr.Chromosome 8 (human)^[1]

End117,540,262 bp^[1]

Quick facts Identifiers, Aliases ...

MED30
Identifiers
Aliases	MED30, MED30S, THRAP6, TRAP25, mediator complex subunit 30
External IDs	OMIM: 610237; MGI: 1917040; HomoloGene: 12329; GeneCards: MED30; OMA:MED30 - orthologs
Gene location (Human) Chr. Chromosome 8 (human)[1] Band 8q24.11 Start 117,520,713 bp[1] End 117,540,262 bp[1]
Gene location (Mouse) Chr. Chromosome 15 (mouse)[2] Band 15|15 C Start 52,575,804 bp[2] End 52,593,960 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in oocyte secondary oocyte bone marrow monocyte ganglionic eminence sperm testicle cartilage tissue Achilles tendon left ovary Top expressed in medial ganglionic eminence zygote interventricular septum endocardial cushion secondary oocyte primary oocyte granulocyte atrioventricular valve thymus lens More reference expression data BioGPS n/a
Gene ontology Molecular function transcription coregulator activity vitamin D receptor binding thyroid hormone receptor binding nuclear receptor coactivator activity ubiquitin protein ligase activity protein binding signaling receptor activity Cellular component nucleoplasm nucleus mediator complex ubiquitin ligase complex Biological process transcription, DNA-templated androgen receptor signaling pathway stem cell population maintenance intracellular steroid hormone receptor signaling pathway positive regulation of transcription, DNA-templated protein ubiquitination regulation of transcription, DNA-templated transcription initiation from RNA polymerase II promoter regulation of transcription by RNA polymerase II Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 90390 69790 Ensembl ENSG00000164758 ENSMUSG00000038622 UniProt Q96HR3 Q9CQI9 RefSeq (mRNA) NM_001282986 NM_080651 NM_001363182 NM_027212 RefSeq (protein) NP_001269915 NP_542382 NP_001350111 NP_081488 Location (UCSC) Chr 8: 117.52 – 117.54 Mb Chr 15: 52.58 – 52.59 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Close