METTL2B

Methyltransferase-like protein 2B is an enzyme that in humans is encoded by the METTL2B gene.^[5][6]

AliasesMETTL2B, METL, METTL2, METTL2A, PSENIP1, methyltransferase like 2B, methyltransferase 2B, methylcytidine

External IDsOMIM: 607846; MGI: 1289171; HomoloGene: 130696; GeneCards: METTL2B; OMA:METTL2B - orthologs

Chr.Chromosome 7 (human)^[1]

End128,506,602 bp^[1]

Quick facts Identifiers, Aliases ...

METTL2B
Identifiers
Aliases	METTL2B, METL, METTL2, METTL2A, PSENIP1, methyltransferase like 2B, methyltransferase 2B, methylcytidine
External IDs	OMIM: 607846; MGI: 1289171; HomoloGene: 130696; GeneCards: METTL2B; OMA:METTL2B - orthologs
Gene location (Human) Chr. Chromosome 7 (human)[1] Band 7q32.1 Start 128,476,729 bp[1] End 128,506,602 bp[1]
Gene location (Mouse) Chr. Chromosome 11 (mouse)[2] Band 11 E1|11 68.61 cM Start 105,017,251 bp[2] End 105,031,220 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in epithelium of colon cerebellar vermis islet of Langerhans quadriceps femoris muscle skeletal muscle tissue gonad endometrium tonsil stromal cell of endometrium muscle of thigh Top expressed in otic vesicle hand spermatocyte tail of embryo epiblast Rostral migratory stream abdominal wall primitive streak embryo ventricular zone More reference expression data BioGPS More reference expression data
Orthologs Species Human Mouse Entrez 55798 52686 Ensembl ENSG00000165055 ENSMUSG00000020691 UniProt Q6P1Q9 Q8BMK1 RefSeq (mRNA) NM_018396 NM_172567 RefSeq (protein) NP_060866 NP_766155 Location (UCSC) Chr 7: 128.48 – 128.51 Mb Chr 11: 105.02 – 105.03 Mb PubMed search [3] [4]
Wikidata
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This gene is a member of a family of methyltransferases that share homology with, but are distinct from, the UbiE family of methyltransferases. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized.^[6]