MEX3D

Protein-coding gene in the species Homo sapiens From Wikipedia, the free encyclopedia

Mex-3 homolog D (C. elegans), also known as MEX3D, is a protein that in humans is encoded by the MEX3D gene.[5][6]

PDBOrtholog search: PDBe RCSB
AliasesMEX3D, MEX-3D, MEX3, OK/SW-cl.4, RKHD1, RNF193, TINO, mex-3 RNA binding family member D
Quick facts Available structures, PDB ...
MEX3D
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesMEX3D, MEX-3D, MEX3, OK/SW-cl.4, RKHD1, RNF193, TINO, mex-3 RNA binding family member D
External IDsOMIM: 611009; MGI: 2681847; HomoloGene: 16890; GeneCards: MEX3D; OMA:MEX3D - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001174118
NM_203304

NM_198615

RefSeq (protein)

NP_001167589
NP_976049

NP_941017

Location (UCSC)Chr 19: 1.55 – 1.57 MbChr 10: 80.22 – 80.22 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse
Close

Function

MEX3D is an RNA binding protein that interacts with AU-rich elements of Bcl-2. Upon binding, MEX3D has a negative regulatory action on Bcl-2 expression at the posttranscriptional level.[6]

Structure

MEX3 proteins contain two N-terminal heterogeneous nuclear ribonucleoprotein K homology motifs (KH domain) and a RING domain at the C-terminus.[6]

References

Further reading

Related Articles

Wikiwand AI