MMP23B

Protein-coding gene in the species Homo sapiens From Wikipedia, the free encyclopedia

Matrix metalloproteinase-23 is an enzyme that in humans is encoded by the MMP23B gene.[5][6][7]

AliasesMMP23B, MIFR, MIFR-1, MMP22, MMP23A, matrix metallopeptidase 23B
End1,635,263 bp[1]
Quick facts Identifiers, Aliases ...
MMP23B
Identifiers
AliasesMMP23B, MIFR, MIFR-1, MMP22, MMP23A, matrix metallopeptidase 23B
External IDsOMIM: 603321; MGI: 1347361; HomoloGene: 3424; GeneCards: MMP23B; OMA:MMP23B - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_006983

NM_011985
NM_001320235

RefSeq (protein)

NP_008914

NP_001307164
NP_036115

Location (UCSC)Chr 1: 1.63 – 1.64 MbChr 4: 155.74 – 155.74 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse
Close

Function

This gene (MMP23B) encodes a member of the matrix metalloproteinase (MMP) family, and it is part of a duplicated region of chromosome 1p36.3. Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. This gene belongs to the copy of the duplicated region of the gene that is closer to the end of the chromosome (more telemeric).[7]

MMP23B is strongly expressed in ovary and heart.[8]

References

Further reading

Related Articles

Wikiwand AI