MORC3

MORC family CW-type zinc finger protein 3 is a protein that in humans is encoded by the MORC3 gene.^[5][6]

PDBOrtholog search: PDBe RCSB

AliasesMORC3, NXP2, ZCW5, ZCWCC3, MORC family CW-type zinc finger 3

External IDsOMIM: 610078; MGI: 2136841; HomoloGene: 32257; GeneCards: MORC3; OMA:MORC3 - orthologs

Chr.Chromosome 21 (human)^[1]

Quick facts Available structures, PDB ...

MORC3
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 4QQ4
Identifiers
Aliases	MORC3, NXP2, ZCW5, ZCWCC3, MORC family CW-type zinc finger 3
External IDs	OMIM: 610078; MGI: 2136841; HomoloGene: 32257; GeneCards: MORC3; OMA:MORC3 - orthologs
Gene location (Human) Chr. Chromosome 21 (human)[1] Band 21q22.12 Start 36,320,189 bp[1] End 36,386,148 bp[1]
Gene location (Mouse) Chr. Chromosome 16 (mouse)[2] Band 16|16 C4 Start 93,629,009 bp[2] End 93,672,961 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in Achilles tendon paraflocculus of cerebellum middle frontal gyrus epithelium of nasopharynx epithelium of colon Brodmann area 10 mucosa of paranasal sinus frontal pole gingival epithelium palpebral conjunctiva Top expressed in spermatocyte primitive streak lymph node otic placode mesenteric lymph nodes granulocyte tail of embryo genital tubercle conjunctival fornix otic vesicle More reference expression data BioGPS More reference expression data
Gene ontology Molecular function zinc ion binding metal ion binding RNA binding protein binding Cellular component nuclear matrix PML body nucleus nucleoplasm Biological process protein phosphorylation protein stabilization viral process negative regulation of fibroblast proliferation post-embryonic development peptidyl-serine phosphorylation maintenance of protein location in nucleus Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 23515 338467 Ensembl ENSG00000159256 ENSMUSG00000039456 UniProt Q14149 F7BJB9 RefSeq (mRNA) NM_015358 NM_001320445 NM_001320446 NM_001045529 RefSeq (protein) NP_001307374 NP_001307375 NP_056173 NP_001038994 Location (UCSC) Chr 21: 36.32 – 36.39 Mb Chr 16: 93.63 – 93.67 Mb PubMed search [3] [4]
Wikidata
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This gene encodes a protein that localizes to the nuclear matrix. The protein also has RNA binding activity, and has a predicted coiled-coil domain.^[6]