MRS8209

MRS8209
Identifiers
	IUPAC name 4-[6-(cyclopentylamino)-2-iodopurin-9-yl]-2,3-dihydroxybicyclo[3.1.0]hexane-1-carbonitrile;
Chemical and physical data
Formula	C17H19IN6O2
Molar mass	466.283 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES O[C@H]1[C@@H](O)[C@@H]([C@H]2C[C@]21C#N)n1cnc2c1nc(I)nc2NC1CCCC1;

MRS8209 is an experimental drug which acts as a potent, peripherally selective 5-HT_2B receptor antagonist with high selectivity over other serotonin receptor subtypes. It has been investigated for possible applications in the treatment of heart and lung fibrosis and intestinal or vascular conditions mediated by 5-HT_2B, while sparing 5-HT_2B mediated activity in the brain.^[1]

FormulaC₁₇H₁₉IN₆O₂

Molar mass466.283 g·mol⁻¹

3D model (JSmol)

Interactive image

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MRS8209

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Identifiers

IUPAC name 4-[6-(cyclopentylamino)-2-iodopurin-9-yl]-2,3-dihydroxybicyclo[3.1.0]hexane-1-carbonitrile
Chemical and physical data
Formula	C₁₇H₁₉IN₆O₂
Molar mass	466.283 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES O[C@H]1[C@@H](O)[C@@H]([C@H]2C[C@]21C#N)n1cnc2c1nc(I)nc2NC1CCCC1