MSP-1014

Psychedelic drug From Wikipedia, the free encyclopedia

MSP-1014 is a serotonergic psychedelic which is under development for the treatment of major depressive disorder, other depressive disorders, and anxiety disorders.[3][4][5][1][2]

It is a prodrug of psilocin similarly to psilocybin, and hence acts as a non-selective serotonin receptor agonist, including of the serotonin 5-HT2A receptor.[3][5][2][6]

The drug is under development by Mindset Pharma and Otsuka America Pharmaceutical.[3][4][5] As of January 2024, it is in phase 2 clinical trials for major depressive disorder and is in the preclinical stage of development for anxiety disorders and other depressive disorders.[3][4][5] The chemical structure of MSP-1014 does not yet seem to have been disclosed.[3][4] However, Mindset Pharma patented psilocin derivatives and prodrugs in 2022.[7]

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