MTSS1

MTSS1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2D1K
Identifiers
Aliases	MTSS1, MIM, MIMA, MIMB, metastasis suppressor 1, I-BAR domain containing, MTSS I-BAR domain containing 1
External IDs	OMIM: 608486; MGI: 2384818; HomoloGene: 8841; GeneCards: MTSS1; OMA:MTSS1 - orthologs
Gene location (Human)
Chr.	Chromosome 8 (human)
End	124,728,473 bp
Gene location (Mouse)
Chr.	Chromosome 15 (mouse)
End	58,953,854 bp
RNA expression pattern
	Top expressed in
	retinal pigment epithelium; ; glomerulus; ; metanephric glomerulus; ; hair follicle; ; subthalamic nucleus; ; renal medulla; ; skin of hip; ; inferior ganglion of vagus nerve; ; skin of thigh; ; bronchial epithelial cell;
	Top expressed in
	lobe of cerebellum; ; cerebellar vermis; ; Rostral migratory stream; ; vestibular membrane of cochlear duct; ; stroma of bone marrow; ; zygote; ; habenula; ; secondary oocyte; ; pineal gland; ; iris;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	actin monomer binding; protein binding; identical protein binding; actin binding; signaling receptor binding;
Cellular component	cytoplasm; ruffle; endocytic vesicle; actin cytoskeleton; cytoskeleton;
Biological process	renal tubule morphogenesis; nephron tubule epithelial cell differentiation; transmembrane receptor protein tyrosine kinase signaling pathway; cellular response to fluid shear stress; cell adhesion; epithelial cell proliferation involved in renal tubule morphogenesis; microspike assembly; negative regulation of epithelial cell proliferation; plasma membrane organization; actin cytoskeleton organization; glomerulus morphogenesis;
	Sources:Amigo / QuickGO
Orthologs
	9788
	211401
	ENSG00000170873
	ENSMUSG00000022353
	O43312
	Q8R1S4
NM_001282971; NM_001282974; NM_014751; NM_001363294; NM_001363295;
	NM_001363296; NM_001363297; NM_001363298; NM_001363299; NM_001363300; NM_001363301; NM_001363302
	NM_001146180; NM_144800
NP_001269900; NP_001269903; NP_055566; NP_001350223; NP_001350224;
	NP_001350225; NP_001350226; NP_001350227; NP_001350228; NP_001350229; NP_001350230; NP_001350231
NP_001139652; NP_659049; NP_001390427; NP_001390428; NP_001390429;
	NP_001390430; NP_001390431; NP_001390432; NP_001390433; NP_001390434; NP_001390435; NP_001390436
	Wikidata
View/Edit Human	View/Edit Mouse

Metastasis suppressor protein 1 is a protein that in humans is encoded by the MTSS1 gene.^[5]^[6]^[7] True to its name, it codes for a metastasis suppressor.