MYH8

MYH8
Identifiers
Aliases	MYH8, MyHC-peri, MyHC-pn, gtMHC-F, DA7, myosin, heavy chain 8, skeletal muscle, perinatal, myosin heavy chain 8
External IDs	OMIM: 160741; MGI: 1339712; GeneCards: MYH8
Gene location (Human)
Chr.	Chromosome 17 (human)
End	10,421,950 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	67,199,460 bp
RNA expression pattern
	Top expressed in
	vastus lateralis muscle; ; Skeletal muscle tissue of rectus abdominis; ; triceps brachii muscle; ; Skeletal muscle tissue of biceps brachii; ; tibialis anterior muscle; ; deltoid muscle; ; glutes; ; testicle; ; kidney tubule; ; gastrocnemius muscle;
	Top expressed in
	masseter muscle; ; esophagus; ; fossa; ; temporal muscle; ; human fetus; ; extraocular muscle; ; internal carotid artery; ; ankle joint; ; muscle of thigh; ; condyle;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	myosin light chain binding; nucleotide binding; microfilament motor activity; structural constituent of muscle; ATPase activity; cytoskeletal motor activity; actin binding; ATP binding; calmodulin binding; myosin phosphatase activity; actin filament binding; microtubule motor activity; microtubule binding;
Cellular component	cytoplasm; myosin filament; cytosol; muscle myosin complex; sarcomere; myofibril; myosin complex;
Biological process	skeletal muscle contraction; ATP metabolic process; muscle contraction; muscle filament sliding; protein dephosphorylation; microtubule-based movement;
	Sources:Amigo / QuickGO
Orthologs
Databases	NCBI: entry; OMA: entry
	4626
	17885
	ENSG00000133020
	ENSMUSG00000055775
	P13535
	P13542
	NM_002472
	NM_177369
	NP_002463
	NP_796343
	Wikidata
View/Edit Human	View/Edit Mouse

Myosin-8, or myosin heavy chain 8, is a protein that is encoded by the MYH8 gene.^[5]^[6] Myosins are proteins found in muscle, composed of two heavy chains and two light chains^[7].