Mir-451 microRNA
RNA family
From Wikipedia, the free encyclopedia
In molecular biology mir-451 microRNA is a short RNA molecule. MicroRNAs function to regulate the expression levels of other genes by several mechanisms.
| mir-451 | |
|---|---|
miR-451 microRNA secondary structure and sequence conservation | |
| Identifiers | |
| Symbol | mir-451 |
| Rfam | RF00722 |
| miRBase family | MIPF0000148 |
| OMIM | 612071 |
| Other data | |
| RNA type | microRNA |
| Domain(s) | Eukaryota; Vertebrata |
| PDB structures | PDBe |
miR-451 regulates the drug-transporter protein P-glycoprotein, potentially promoting resistance to the chemotherapy drug Paclitaxel.[1]
Applications
A proof-of-concept experiment has shown that miR-451, as well as mir-126 and mir-150, could be using in forensic science to distinguish between blood and saliva samples.[2] This is made possible by different miRNA profiles of miRNAs in the different tissue types.[2]
