Monometacrine

Abandoned antidepressant From Wikipedia, the free encyclopedia

Monometacrine (INNTooltip International Nonproprietary Name; developmental code name SD-735), also known as desmethyldimetacrine, is a drug of the tricyclic family described as an antidepressant which was never marketed.[1][2][3] It was first described in the literature by 1966.[1] The drug is the N-desmethyl analogue of dimetacrine and is a metabolite of dimetacrine.[1][3]

Other namesDesmethyldimetacrine; Nordimetacrine; N-Desmethyldimetacrine; SD-735; NSC-100296
CAS Number
Quick facts Clinical data, Other names ...
Monometacrine
Clinical data
Other namesDesmethyldimetacrine; Nordimetacrine; N-Desmethyldimetacrine; SD-735; NSC-100296
Identifiers
  • 3-(9,9-dimethylacridin-10-yl)-N-methylpropan-1-amine
CAS Number
PubChem CID
ChemSpider
UNII
ChEMBL
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC19H24N2
Molar mass280.415 g·mol−1
3D model (JSmol)
  • CC1(C2=CC=CC=C2N(C3=CC=CC=C31)CCCNC)C
  • InChI=1S/C19H24N2/c1-19(2)15-9-4-6-11-17(15)21(14-8-13-20-3)18-12-7-5-10-16(18)19/h4-7,9-12,20H,8,13-14H2,1-3H3
  • Key:PGSOFANFWNSSRA-UHFFFAOYSA-N
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