NDC80

NDC80
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2IGP, 2VE7, 3IZ0
Identifiers
Aliases	NDC80, HEC, HEC1, HsHec1, KNTC2, TID3, hskinetochore complex component, NDC80 kinetochore complex component
External IDs	OMIM: 607272; MGI: 1914302; HomoloGene: 38141; GeneCards: NDC80; OMA:NDC80 - orthologs
Gene location (Human)
Chr.	Chromosome 18 (human)
End	2,616,635 bp
Gene location (Mouse)
Chr.	Chromosome 17 (mouse)
End	71,833,852 bp
RNA expression pattern
	Top expressed in
	ventricular zone; ; ganglionic eminence; ; gonad; ; testicle; ; trabecular bone; ; amniotic fluid; ; bone marrow; ; secondary oocyte; ; sperm; ; seminal vesicula;
	Top expressed in
	zygote; ; secondary oocyte; ; tail of embryo; ; genital tubercle; ; primary oocyte; ; spermatocyte; ; ventricular zone; ; epiblast; ; maxillary prominence; ; mandibular prominence;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	structural constituent of cytoskeleton; protein binding; identical protein binding;
Cellular component	cytosol; membrane; chromosome; Ndc80 complex; chromosome, centromeric region; nucleus; kinetochore; nucleoplasm; centrosome;
Biological process	chromosome segregation; mitotic spindle organization; cell division; establishment of mitotic spindle orientation; mitotic sister chromatid segregation; cell cycle; attachment of spindle microtubules to kinetochore; sister chromatid cohesion; metaphase plate congression; attachment of mitotic spindle microtubules to kinetochore; positive regulation of mitotic cell cycle spindle assembly checkpoint; mitotic cell cycle; kinetochore organization; positive regulation of protein localization to kinetochore;
	Sources:Amigo / QuickGO
Orthologs
	10403
	67052
	ENSG00000080986
	ENSMUSG00000024056
	O14777
	Q9D0F1
	NM_006101
	NM_023294
	NP_006092
	NP_075783
	Wikidata
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