NDRG2
Protein-coding gene in humans
From Wikipedia, the free encyclopedia
Protein NDRG2 is a protein that in humans is encoded by the NDRG2 gene (NMYC downstream-regulated gene 2).[5][6]
External IDsOMIM: 605272; MGI: 1352498; HomoloGene: 22785; GeneCards: NDRG2; OMA:NDRG2 - orthologs
Function
This gene is a member of the N-myc downregulated gene family which belongs to the alpha/beta hydrolase superfamily. The protein encoded by this gene is a cytoplasmic protein that may play a role in neurite outgrowth. This gene may be involved in glioblastoma and aggressive meningioma carcinogenesis (via cell proliferation[7]).[8] Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.[6]
