NLRP14

NLRP14
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	4N1J, 4N1K, 4N1L
Identifiers
Aliases	NLRP14, CLR11.2, GC-LRR, NALP14, NOD5, PAN8, NLR family, pyrin domain containing 14, NLR family pyrin domain containing 14
External IDs	OMIM: 609665; MGI: 1924108; HomoloGene: 18531; GeneCards: NLRP14; OMA:NLRP14 - orthologs
Gene location (Human)
Chr.	Chromosome 11 (human)
End	7,071,526 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	106,797,309 bp
RNA expression pattern
	Top expressed in
	oocyte; ; secondary oocyte; ; testicle; ; bone marrow cell; ; ventricular zone; ; olfactory zone of nasal mucosa; ; ganglionic eminence; ; liver; ; human kidney; ; spinal cord;
	Top expressed in
	primary oocyte; ; secondary oocyte; ; zygote; ; spermatid; ; spermatocyte; ; seminiferous tubule; ; morula; ; embryo; ; ovary; ; blastocyst;
	More reference expression data
	n/a
Gene ontology
Molecular function	ATP binding; nucleotide binding;
Cellular component	cytoplasm;
Biological process	cell differentiation; multicellular organism development; spermatogenesis;
	Sources:Amigo / QuickGO
Orthologs
	338323
	76858
	ENSG00000158077
	ENSMUSG00000016626
	Q86W24
	Q6B966
	NM_176822
	NM_001002894
	NP_789792
	NP_001002894
	Wikidata
View/Edit Human	View/Edit Mouse

NLRP14, short for NOD-like receptor family pyrin domain containing 14, is an intracellular protein of mammals associated with a role in spermatogenesis. It is also known as NALP14, NOD5, GC-LRR, Nalp-iota, PAN8, and CLR11.2, and is one of 14 pyrin domain containing members of the NOD-like receptor family of cytoplasmic receptors.^[5] NLRP14 is found exclusively in the testes where it is expressed within spermatogonia, spermatocytes and spermatids.^[6]