NOM1

Nucleolar protein with MIF4G domain 1 is a protein that in humans is encoded by the NOM1 gene.^[5]

AliasesNOM1, C7orf3, PPP1R113, SGD1, nucleolar protein with MIF4G domain 1

External IDsOMIM: 611269; MGI: 1861749; HomoloGene: 39776; GeneCards: NOM1; OMA:NOM1 - orthologs

Chr.Chromosome 7 (human)^[1]

End156,973,176 bp^[1]

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NOM1
Identifiers
Aliases	NOM1, C7orf3, PPP1R113, SGD1, nucleolar protein with MIF4G domain 1
External IDs	OMIM: 611269; MGI: 1861749; HomoloGene: 39776; GeneCards: NOM1; OMA:NOM1 - orthologs
Gene location (Human) Chr. Chromosome 7 (human)[1] Band 7q36.3 Start 156,949,712 bp[1] End 156,973,176 bp[1]
Gene location (Mouse) Chr. Chromosome 5 (mouse)[2] Band 5 B1|5 15.0 cM Start 29,639,662 bp[2] End 29,662,841 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in pancreatic epithelial cell visceral pleura germinal epithelium parietal pleura gingival epithelium body of pancreas skin of abdomen epithelium of colon skin of leg gonad Top expressed in spermatocyte epiblast ovary ventricular zone placenta spermatid liver ganglionic eminence tail of embryo thymus More reference expression data BioGPS n/a
Gene ontology Molecular function protein binding RNA binding Cellular component nucleolus nucleus Biological process neurogenesis ribosomal small subunit biogenesis hair follicle maturation biological process Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 64434 433864 Ensembl ENSG00000146909 ENSMUSG00000001569 UniProt Q5C9Z4 Q3UFM5 RefSeq (mRNA) NM_138400 NM_001353366 NM_001033457 RefSeq (protein) NP_612409 NP_001340295 NP_001028629 Location (UCSC) Chr 7: 156.95 – 156.97 Mb Chr 5: 29.64 – 29.66 Mb PubMed search [3] [4]
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Proteins that contain MIF4G (middle of eIF4G (MIM 600495)) and/or MA3 domains, such as NOM1, function in protein translation. These domains include binding sites for members of the EIF4A family of ATP-dependent DEAD box RNA helicases.^[6][5]