NOX5
Protein-coding gene in the species Homo sapiens
From Wikipedia, the free encyclopedia
NADPH oxidase, EF-hand calcium binding domain 5, also known as NOX5, is a protein which in humans is encoded by the NOX5 gene.[3][4]
External IDsOMIM: 606572; HomoloGene: 41568; GeneCards: NOX5; OMA:NOX5 - orthologs
Function
NOX5 is a novel NADPH oxidase that generates superoxide.[3]
Nox5 interacts with c-abl, superoxide production leads to phosphorylation of c-abl, while inhibition of c-abl kinase activity inhibits Nox5 superoxide production.[5]