NUTF2

Protein-coding gene in the species Homo sapiens From Wikipedia, the free encyclopedia

Nuclear transport factor 2 is a protein that in humans is encoded by the NUTF2 gene.[4][5][6]

PDBOrtholog search: PDBe RCSB
AliasesNUTF2, NTF2, PP15, NTF-2, nuclear transport factor 2
Quick facts Available structures, PDB ...
NUTF2
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesNUTF2, NTF2, PP15, NTF-2, nuclear transport factor 2
External IDsOMIM: 605813; MGI: 3704482; HomoloGene: 110745; GeneCards: NUTF2; OMA:NUTF2 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_005796
NM_001322038
NM_001322039
NM_001322040
NM_001322041

XM_001473957

RefSeq (protein)

NP_080808
NP_001344158
NP_001344159

Location (UCSC)Chr 16: 67.85 – 67.87 Mbn/a
PubMed search[2][3]
Wikidata
View/Edit HumanView/Edit Mouse
Close

Function

The protein encoded by this gene is a cytosolic factor that facilitates protein transport into the nucleus. It interacts with the nuclear pore complex glycoprotein p62. This encoded protein acts at a relative late stage of nuclear protein import, subsequent to the initial docking of nuclear import ligand at the nuclear envelope. It is thought to be part of a multicomponent system of cytosolic factors that assemble at the pore complex during nuclear import.[6]

Interactions

NUTF2 has been shown to interact with Nucleoporin 62[4][7] and RAN.[8][9]

References

Further reading

Related Articles

Wikiwand AI