NUCKS1

Nuclear ubiquitous casein and cyclin-dependent kinases substrate is a protein that in humans is encoded by the NUCKS1 gene.^[5][6]

AliasesNUCKS1, NUCKS, JC7, nuclear casein kinase and cyclin-dependent kinase substrate 1, nuclear casein kinase and cyclin dependent kinase substrate 1

External IDsOMIM: 611912; MGI: 1934811; HomoloGene: 23377; GeneCards: NUCKS1; OMA:NUCKS1 - orthologs

Chr.Chromosome 1 (human)^[1]

End205,750,182 bp^[1]

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NUCKS1
Identifiers
Aliases	NUCKS1, NUCKS, JC7, nuclear casein kinase and cyclin-dependent kinase substrate 1, nuclear casein kinase and cyclin dependent kinase substrate 1
External IDs	OMIM: 611912; MGI: 1934811; HomoloGene: 23377; GeneCards: NUCKS1; OMA:NUCKS1 - orthologs
Gene location (Human) Chr. Chromosome 1 (human)[1] Band 1q32.1 Start 205,712,822 bp[1] End 205,750,182 bp[1]
Gene location (Mouse) Chr. Chromosome 1 (mouse)[2] Band 1|1 E4 Start 131,838,272 bp[2] End 131,864,059 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in tendon of biceps brachii parietal pleura internal globus pallidus germinal epithelium visceral pleura middle temporal gyrus external globus pallidus pars reticulata seminal vesicula tibia Top expressed in Rostral migratory stream primitive streak ciliary body abdominal wall migratory enteric neural crest cell dermis Gonadal ridge renal corpuscle internal carotid artery vas deferens More reference expression data BioGPS More reference expression data
Gene ontology Molecular function DNA-binding transcription activator activity, RNA polymerase II-specific transcription factor binding chromatin binding double-stranded DNA binding single-stranded DNA binding RNA binding Cellular component cytoplasm nucleus chromatin nucleolus Biological process positive regulation of insulin receptor signaling pathway transcription by RNA polymerase II glucose homeostasis positive regulation of transcription by RNA polymerase II interstrand cross-link repair regulation of DNA strand elongation cellular response to X-ray regulation of DNA replication gene conversion double-strand break repair via homologous recombination regulation of transcription by RNA polymerase II replication fork processing cellular glucose homeostasis chromatin organization regulation of insulin receptor signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 64710 98415 Ensembl ENSG00000069275 ENSMUSG00000026434 UniProt Q9H1E3 Q80XU3 RefSeq (mRNA) NM_022731 NM_001145804 NM_175294 RefSeq (protein) NP_073568 NP_001139276 NP_780503 Location (UCSC) Chr 1: 205.71 – 205.75 Mb Chr 1: 131.84 – 131.86 Mb PubMed search [3] [4]
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