Nucleoporin 54

Protein-coding gene in the species Homo sapiens From Wikipedia, the free encyclopedia

Nucleoporin 54 (Nup54) is a protein that in humans is encoded by the NUP54 gene.[5][6]

Quick facts NUP54, Available structures ...
NUP54
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesNUP54, nucleoporin 54
External IDsOMIM: 607607; MGI: 1920460; HomoloGene: 41169; GeneCards: NUP54; OMA:NUP54 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001278603
NM_017426

NM_183392
NM_001359995

RefSeq (protein)

NP_001265532
NP_059122

NP_899248
NP_001346924

Location (UCSC)Chr 4: 76.11 – 76.15 MbChr 5: 92.56 – 92.58 Mb
PubMed search[3][4]
Wikidata
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Function

The nuclear envelope creates distinct nuclear and cytoplasmic compartments in eukaryotic cells. It consists of two concentric membranes perforated by nuclear pores, large protein complexes that form aqueous channels to regulate the flow of macromolecules between the nucleus and the cytoplasm. These complexes are composed of at least 100 different polypeptide subunits, many of which belong to the nucleoporin family. This gene encodes a member of the phe-gly (FG) repeat-containing nucleoporin subset.[6]

References

Further reading

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