Ninein
Protein in humans and other animals
From Wikipedia, the free encyclopedia
Ninein is a protein that in humans is encoded by the NIN gene.[5][6][7]
External IDsOMIM: 608684; MGI: 105108; HomoloGene: 40632; GeneCards: NIN; OMA:NIN - orthologs
Function
Ninein, together with its paralog Ninein-like protein is one of the proteins important for centrosomal function. Localization of this protein to the centrosome requires three leucine zippers in the central coiled-coil domain. Multiple alternatively spliced transcript variants that encode different isoforms have been reported.[7]
This protein is important for positioning and anchoring the microtubules minus-ends in epithelial cells.[7]