Ninein

Protein in humans and other animals From Wikipedia, the free encyclopedia

Ninein is a protein that in humans is encoded by the NIN gene.[5][6][7]

Quick facts NIN, Identifiers ...
NIN
Identifiers
AliasesNIN, SCKL7, ninein
External IDsOMIM: 608684; MGI: 105108; HomoloGene: 40632; GeneCards: NIN; OMA:NIN - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_016350
NM_020921
NM_182944
NM_182945
NM_182946

NM_001081453
NM_001286079
NM_001286080
NM_008697

RefSeq (protein)

NP_057434
NP_065972
NP_891989
NP_891991

NP_001074922
NP_001273008
NP_001273009
NP_032723
NP_001390761

Location (UCSC)Chr 14: 50.72 – 50.83 MbChr 12: 70.06 – 70.16 Mb
PubMed search[3][4]
Wikidata
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Function

Ninein, together with its paralog Ninein-like protein is one of the proteins important for centrosomal function. Localization of this protein to the centrosome requires three leucine zippers in the central coiled-coil domain. Multiple alternatively spliced transcript variants that encode different isoforms have been reported.[7]

This protein is important for positioning and anchoring the microtubules minus-ends in epithelial cells.[7]

References

Further reading

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