Nitromersol
Organomercury antiseptic and antifungal agent
From Wikipedia, the free encyclopedia
Nitromersol (metaphen) is a mercury-containing organic compound that is primarily used as an antiseptic and disinfectant. It is a brown-yellow solid that has no odor or taste, does not irritate the skin or mucous membranes, and has no impact on rubber or metallic instruments, including surgical and dental tools.[1]
| Names | |
|---|---|
| IUPAC name
5-Methyl-2-nitro-7-oxa-8-mercurabicyclo[4.2.0]octa-1(6),2,4-triene | |
| Other names
Metaphen; 6-Methyl-3-nitrobenzoxamercurete; 4-Nitro-5-hydroxymercuriorthocresol | |
| Identifiers | |
3D model (JSmol) |
|
| ChemSpider | |
| ECHA InfoCard | 100.004.648 |
PubChem CID |
|
| UNII | |
CompTox Dashboard (EPA) |
|
| |
| |
| Properties | |
| C7H5HgNO3 | |
| Molar mass | 351.713 g·mol−1 |
| Hazards | |
| Occupational safety and health (OHS/OSH): | |
Main hazards |
moderately toxic |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
| |
This compound is a confirmed animal carcinogen. It can emit toxic fumes of NOx and mercury vapor when heated.[2] In 1998, use of nitromersol (and other mercury-containing products) as OTC first-aid antiseptics and products for diaper rash and vaginal contraceptives was disallowed by the FDA.[3] Nitromersol can cause hypersensitivity reactions.[4]
It is still in use as a preservative for vaccines and antitoxins.[examples needed][citation needed]
See also
- Thiomersal – Organomercury antiseptic and antifungal agent
- Phenylmercuric nitrate - an organomercury compound with powerful antiseptic and antifungal effects
