Nonabine

Nonabine
Clinical data
ATC code	none;
Legal status
Legal status	Not approved for any medical use;
Identifiers
	IUPAC name 7-(1,2-Dimethylheptyl)-2,2-dimethyl-4-(4-pyridinyl)-2H-1-benzopyran-5-ol;
CAS Number	16985-03-8 ;
PubChem CID	71885;
ChemSpider	64899 ;
UNII	77DUK856J7;
CompTox Dashboard (EPA)	DTXSID20864727 ;
Chemical and physical data
Formula	C25H33NO2
Molar mass	379.544 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CCCCCC(C)C(C)c1cc(c2c(c1)OC(C=C2c3ccncc3)(C)C)O;
	InChI InChI=1S/C25H33NO2/c1-6-7-8-9-17(2)18(3)20-14-22(27)24-21(19-10-12-26-13-11-19)16-25(4,5)28-23(24)15-20/h10-18,27H,6-9H2,1-5H3 ; Key:YHUDSHIRWOVVCV-UHFFFAOYSA-N ;
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Nonabine (BRL-4664) is an experimental drug which is a synthetic THC analog.^[1] It was studied in the 1980s for the prevention of nausea and vomiting associated with cancer chemotherapy but was never marketed.^[1] It has strong antiemetic effects equivalent to those of chlorpromazine, and also produces some mild sedative effects, along with dry mouth and EEG changes typical of cannabinoid agonists, but with minimal changes in mood or perception, suggesting the abuse potential is likely to be low.^[2]^[3]