O-2172

Chemical compound From Wikipedia, the free encyclopedia

O-2172 is a drug developed by Organix Inc, which acts as a stimulant and potent dopamine reuptake inhibitor. It is an analogue of methylphenidate where the phenyl ring has had a 3,4-dichloro substitution added, and the piperidine ring has been replaced by cyclopentane. It is around 1/3 the potency of methylphenidate, demonstrating that even with the important binding group of the nitrogen lone pair removed entirely, selective DAT binding and reuptake inhibition is still possible.[1][2]

CAS Number
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O-2172
Identifiers
  • methyl 2-cyclopentyl-2-(3,4-dichlorophenyl)acetate
CAS Number
PubChem CID
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UNII
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Chemical and physical data
FormulaC14H16Cl2O2
Molar mass287.18 g·mol−1
3D model (JSmol)
  • Clc1ccc(cc1Cl)C(C(=O)OC)C2CCCC2
  • InChI=1S/C14H16Cl2O2/c1-18-14(17)13(9-4-2-3-5-9)10-6-7-11(15)12(16)8-10/h6-9,13H,2-5H2,1H3 ☒N
  • Key:NEHPFNBRZYFWFN-UHFFFAOYSA-N ☒N
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It has been sold as a designer drug under the name DCCPM.[3]

See also

References

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