Odalasvir

Odalasvir
Legal status
Legal status	US: Investigational New Drug;
Identifiers
	IUPAC name Dimethyl N,N'-(1,4(1,4)-dibenzenacyclohexaphane- 12,42-diylbis{1H-benzimidazole-5,2-diyl[(2S,3aS,7aS)- octahydro-1H-indole-2,1-diyl] [(2S)-3-methyl-1-oxobutan- 1,2-diyl]})biscarbamate;
CAS Number	1415119-52-6 ;
PubChem CID	71474517;
ChemSpider	34500837;
UNII	OVR52K7BDW;
CompTox Dashboard (EPA)	DTXSID401032258 ;
Chemical and physical data
Formula	C60H72N8O6
Molar mass	1001.286 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CC(C)[C@@H](C(=O)N1[C@H]2CCCC[C@H]2C[C@H]1C3=NC4=C(N3)C=C(C=C4)C5=C6CCC7=CC(=C(CCC(=C5)C=C6)C=C7)C8=CC9=C(C=C8)N=C(N9)[C@@H]1C[C@@H]2CCCC[C@@H]2N1C(=O)[C@H](C(C)C)NC(=O)OC)NC(=O)OC;
	InChI InChI=1S/C60H72N8O6/c1-33(2)53(65-59(71)73-5)57(69)67-49-13-9-7-11-41(49)31-51(67)55-61-45-25-23-39(29-47(45)63-55)43-27-35-15-19-37(43)21-17-36-16-20-38(22-18-35)44(28-36)40-24-26-46-48(30-40)64-56(62-46)52-32-42-12-8-10-14-50(42)68(52)58(70)54(34(3)4)66-60(72)74-6/h15-16,19-20,23-30,33-34,41-42,49-54H,7-14,17-18,21-22,31-32H2,1-6H3,(H,61,63)(H,62,64)(H,65,71)(H,66,72)/t41-,42-,49-,50-,51-,52-,53-,54-/m0/s1; Key:LSYBRGMTRKJATA-IVEWBXRVSA-N;

Odalasvir (INN,^[1] previously known as ACH-3102)^[2]^[3] is an investigational new drug in development for the treatment of hepatitis C.^[4] It is an NS5A inhibitor.^[5] The NS5A protein serves multiple functions at various stages of the viral life cycle, including viral replication. NS5A also plays a role in the development of interferon-resistance, a common cause of treatment failure.^[6]^[7]^[8] It is under development by Achillion Pharmaceuticals.^[9]