Oxantel

Oxantel is an anthelmintic. It has typically been used in human and animal medicine as a treatment for intestinal worms.^[1] It has also been shown to inhibit fumarate reductase in some pathogenic bacteria.^[2]

ATC code

• P02CC02 (WHO) QP52AF03 (WHO)

CAS Number

• 36531-26-7 ^Y

PubChem CID

• 5281087

ChemSpider

• 4444540 ^N

Quick facts Clinical data, ATC code ...

Oxantel

Clinical data
ATC code	P02CC02 (WHO) QP52AF03 (WHO)
Identifiers
IUPAC name 3-[(E)-2-(1-Methyl-5,6-dihydro-4H-pyrimidin-2-yl)ethenyl]phenol
CAS Number	36531-26-7 Y
PubChem CID	5281087
ChemSpider	4444540 N
UNII	94AJJ30D9E
KEGG	D00806 Y
CompTox Dashboard (EPA)	DTXSID601016597
Chemical and physical data
Formula	C13H16N2O
Molar mass	216.284 g·mol−1
3D model (JSmol)	Interactive image
SMILES CN1CCCN=C1/C=C/C2=CC(=CC=C2)O
InChI InChI=1S/C13H16N2O/c1-15-9-3-8-14-13(15)7-6-11-4-2-5-12(16)10-11/h2,4-7,10,16H,3,8-9H2,1H3/b7-6+ N Key:VRYKTHBAWRESFI-VOTSOKGWSA-N N
NY (what is this?)  (verify)

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Similarly to pyrantel, oxantel depolarises the neurons of gastrointestinal parasites 100x more than acetylcholine, causing sustained muscular contraction, causing the parasites to die by spastic paralysis. This anthelmintic is commonly used to treat domestic animals as well as livestock, and resistance has been reported in both groups of animals.^[3]