Neutrophil cytosolic factor 2

NCF2
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1E96, 1HH8, 1K4U, 1OEY, 1WM5, 2DMO
Identifiers
Aliases	NCF2, NCF-2, NOXA2, P67-PHOX, P67PHOX, Neutrophil cytosolic factor 2
External IDs	OMIM: 608515; MGI: 97284; HomoloGene: 374; GeneCards: NCF2; OMA:NCF2 - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	183,590,876 bp
Gene location (Mouse)
Chr.	Chromosome 1 (mouse)
End	152,712,742 bp
RNA expression pattern
	Top expressed in
	monocyte; ; blood; ; granulocyte; ; bone marrow; ; bone marrow cell; ; right lung; ; spleen; ; trabecular bone; ; upper lobe of left lung; ; periodontal fiber;
	Top expressed in
	granulocyte; ; spleen; ; bone marrow; ; ileum; ; jejunum; ; colon; ; lung; ; ovary; ; uterus; ; thymus;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	superoxide-generating NAD(P)H oxidase activity; protein C-terminus binding; protein binding; electron transfer activity; superoxide-generating NADPH oxidase activator activity;
Cellular component	acrosomal vesicle; nucleolus; phagolysosome; cytoplasm; cytosol; NADPH oxidase complex;
Biological process	superoxide anion generation; cellular defense response; vascular endothelial growth factor receptor signaling pathway; innate immune response; superoxide metabolic process; phagocytosis; positive regulation of catalytic activity; respiratory burst; electron transport chain; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; cellular response to oxidative stress; cell redox homeostasis;
	Sources:Amigo / QuickGO
Orthologs
	4688
	17970
	ENSG00000116701
	ENSMUSG00000026480
	P19878
	O70145
	NM_000433; NM_001127651; NM_001190789; NM_001190794
	NM_010877
	NP_000424; NP_001121123; NP_001177718; NP_001177723
	NP_035007
	Wikidata
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