PAXIP1

PAXIP1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3SQD
Identifiers
Aliases	PAXIP1, CAGF29, PACIP1, PAXIP1L, PTIP, TNRC2, CAGF28, PAX interacting protein 1
External IDs	OMIM: 608254; MGI: 1890430; HomoloGene: 133914; GeneCards: PAXIP1; OMA:PAXIP1 - orthologs
Gene location (Human)
Chr.	Chromosome 7 (human)
End	155,003,124 bp
Gene location (Mouse)
Chr.	Chromosome 5 (mouse)
End	27,996,689 bp
RNA expression pattern
	Top expressed in
	secondary oocyte; ; cerebellar hemisphere; ; ventricular zone; ; right hemisphere of cerebellum; ; corpus epididymis; ; thymus; ; cerebellar vermis; ; cartilage tissue; ; embryo; ; ganglionic eminence;
	Top expressed in
	tail of embryo; ; genital tubercle; ; epiblast; ; ventricular zone; ; zygote; ; islet of Langerhans; ; thymus; ; otic placode; ; spermatid; ; primitive streak;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein binding;
Cellular component	nuclear matrix; nucleoplasm; MLL3/4 complex; nucleus; histone methyltransferase complex; chromosome;
Biological process	response to ionizing radiation; positive regulation of histone H3-K36 methylation; DNA recombination; regulation of transcription, DNA-templated; chorion development; DNA damage response, signal transduction by p53 class mediator; transcription, DNA-templated; positive regulation of histone acetylation; cellular response to DNA damage stimulus; vasculogenesis; positive regulation of isotype switching; histone H3-K4 methylation; positive regulation of histone H3-K4 methylation; adipose tissue development; double-strand break repair via nonhomologous end joining; positive regulation of protein ubiquitination; endothelial cell migration; DNA repair; positive regulation of transcription initiation from RNA polymerase II promoter; regulation of cell cycle G2/M phase transition; positive regulation of isotype switching to IgG isotypes; positive regulation of response to DNA damage stimulus; negative regulation of DNA-binding transcription factor activity;
	Sources:Amigo / QuickGO
Orthologs
	22976
	55982
	ENSG00000157212
	ENSMUSG00000002221
	Q6ZW49
	Q6NZQ4
	NM_007349
	NM_018878
	NP_031375
	NP_061366
	Wikidata
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