PBX2
Protein found in humans
From Wikipedia, the free encyclopedia
Pre-B-cell leukemia transcription factor 2 is a protein that in humans is encoded by the PBX2 gene.[5][6]
External IDsOMIM: 176311; MGI: 1341793; HomoloGene: 48115; GeneCards: PBX2; OMA:PBX2 - orthologs
Function
This gene encodes a ubiquitously expressed member of the TALE/PBX homeobox family. It was identified by its similarity to a homeobox gene which is involved in t(1;19) translocation in acute pre-B-cell leukemias. This protein is a transcriptional activator which binds to the TLX1 promoter. The gene is located within the major histocompatibility complex (MHC) on chromosome 6.[6]