PCDH7

Protocadherin-7 is a protein that in humans is encoded by the PCDH7 gene.^[5][6]

PDBHuman UniProt search: PDBe RCSB

AliasesPCDH7, BH-Pcdh, BHPCDH, PPP1R120, protocadherin 7

External IDsOMIM: 602988; MGI: 1860487; HomoloGene: 36101; GeneCards: PCDH7; OMA:PCDH7 - orthologs

Chr.Chromosome 4 (human)^[1]

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PCDH7
Available structures PDB Human UniProt search: PDBe RCSB List of PDB id codes 2YST
Identifiers
Aliases	PCDH7, BH-Pcdh, BHPCDH, PPP1R120, protocadherin 7
External IDs	OMIM: 602988; MGI: 1860487; HomoloGene: 36101; GeneCards: PCDH7; OMA:PCDH7 - orthologs
Gene location (Human) Chr. Chromosome 4 (human)[1] Band 4p15.1 Start 30,720,369 bp[1] End 31,146,805 bp[1]
Gene location (Mouse) Chr. Chromosome 5 (mouse)[2] Band 5|5 C1 Start 57,875,309 bp[2] End 58,290,572 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in endothelial cell middle temporal gyrus Brodmann area 23 urethra saphenous vein corpus epididymis seminal vesicula pons entorhinal cortex postcentral gyrus Top expressed in ascending aorta arcuate nucleus anterior amygdaloid area ventromedial nucleus subiculum median eminence paraventricular nucleus of hypothalamus lateral geniculate nucleus aortic valve medial geniculate nucleus More reference expression data BioGPS More reference expression data
Gene ontology Molecular function calcium ion binding Cellular component integral component of membrane plasma membrane integral component of plasma membrane membrane platelet alpha granule membrane Biological process cell adhesion homophilic cell adhesion via plasma membrane adhesion molecules platelet degranulation Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 5099 54216 Ensembl ENSG00000169851 ENSMUSG00000029108 UniProt O60245 n/a RefSeq (mRNA) NM_001173523 NM_002589 NM_032456 NM_032457 NM_001122758 NM_018764 NM_001310606 NM_001310608 RefSeq (protein) NP_001166994 NP_002580 NP_115832 NP_115833 n/a Location (UCSC) Chr 4: 30.72 – 31.15 Mb Chr 5: 57.88 – 58.29 Mb PubMed search [3] [4]
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This gene belongs to the protocadherin gene family, a subfamily of the cadherin superfamily. The gene encodes a protein with an extracellular domain containing 7 cadherin repeats. The gene product is an integral membrane protein that is thought to function in cell–cell recognition and adhesion. Alternative splicing yields isoforms with unique cytoplasmic tails.^[6]