PDE6G

PDE6G
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3JWR
Identifiers
Aliases	PDE6G, PDEG, RP57, phosphodiesterase 6G
External IDs	OMIM: 180073; MGI: 97526; HomoloGene: 1955; GeneCards: PDE6G; OMA:PDE6G - orthologs
Gene location (Human)
Chr.	Chromosome 17 (human)
End	81,663,112 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	120,344,326 bp
RNA expression pattern
	Top expressed in
	testicle; ; gonad; ; granulocyte; ; lymph node; ; spleen; ; retinal pigment epithelium; ; monocyte; ; secondary oocyte; ; blood; ; bone marrow cell;
	Top expressed in
	neural layer of retina; ; epithelium of lens; ; pineal gland; ; retinal pigment epithelium; ; corneal stroma; ; gastrula; ; iris; ; outer nuclear layer; ; right ventricle; ; ciliary body;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	enzyme inhibitor activity; spectrin binding; cGMP binding; protein binding; 3',5'-cyclic-GMP phosphodiesterase activity; 3',5'-cyclic-nucleotide phosphodiesterase activity; hydrolase activity;
Cellular component	plasma membrane; photoreceptor disc membrane; photoreceptor outer segment membrane;
Biological process	positive regulation of G protein-coupled receptor signaling pathway; positive regulation of epidermal growth factor receptor signaling pathway; visual perception; response to stimulus; regulation of rhodopsin mediated signaling pathway; negative regulation of catalytic activity; Wnt signaling pathway, calcium modulating pathway; rhodopsin mediated signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	5148
	18588
	ENSG00000185527
	ENSMUSG00000025386
	P18545
	P09174
	NM_002602; NM_001365724; NM_001365725
	NM_012065
	NP_002593; NP_001352653; NP_001352654
	NP_036197
	Wikidata
View/Edit Human	View/Edit Mouse

Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma is an enzyme that in humans is encoded by the PDE6G gene.^[5]^[6]^[7]