PDE6G

PDE6G
Identifiers
Aliases	PDE6G, PDEG, RP57, phosphodiesterase 6G
External IDs	OMIM: 180073; MGI: 97526; GeneCards: PDE6G
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3JWR
Gene location (Human)
Chr.	Chromosome 17 (human)
End	81,663,112 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	120,344,326 bp
RNA expression pattern
	Top expressed in
	testicle; ; gonad; ; granulocyte; ; lymph node; ; spleen; ; retinal pigment epithelium; ; monocyte; ; secondary oocyte; ; blood; ; bone marrow cell;
	Top expressed in
	neural layer of retina; ; epithelium of lens; ; pineal gland; ; retinal pigment epithelium; ; corneal stroma; ; gastrula; ; iris; ; outer nuclear layer; ; right ventricle; ; ciliary body;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	enzyme inhibitor activity; spectrin binding; cGMP binding; protein binding; 3',5'-cyclic-GMP phosphodiesterase activity; 3',5'-cyclic-nucleotide phosphodiesterase activity; hydrolase activity;
Cellular component	plasma membrane; photoreceptor disc membrane; photoreceptor outer segment membrane;
Biological process	positive regulation of G protein-coupled receptor signaling pathway; positive regulation of epidermal growth factor receptor signaling pathway; visual perception; response to stimulus; regulation of rhodopsin mediated signaling pathway; negative regulation of catalytic activity; Wnt signaling pathway, calcium modulating pathway; rhodopsin mediated signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
Databases	NCBI: entry; OMA: entry
	5148
	18588
	ENSG00000185527
	ENSMUSG00000025386
	P18545
	P09174
	NM_002602; NM_001365724; NM_001365725
	NM_012065
	NP_002593; NP_001352653; NP_001352654
	NP_036197
	Wikidata
View/Edit Human	View/Edit Mouse

Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma is an enzyme that in humans is encoded by the PDE6G gene.^[5]^[6]^[7]