PFDN4

Protein-coding gene in the species Homo sapiens From Wikipedia, the free encyclopedia

Prefoldin subunit 4 is a protein that in humans is encoded by the PFDN4 gene.[5][6][7]

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PFDN4
Identifiers
AliasesPFDN4, C1, PFD4, prefoldin subunit 4
External IDsOMIM: 604898; MGI: 1923512; HomoloGene: 37645; GeneCards: PFDN4; OMA:PFDN4 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_002623

NM_001013369
NM_001110152
NM_001199902

RefSeq (protein)

NP_002614

n/a

Location (UCSC)Chr 20: 54.21 – 54.23 MbChr 2: 170.34 – 170.36 Mb
PubMed search[3][4]
Wikidata
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Function

This gene encodes a member of the prefoldin beta subunit family. The encoded protein is one of six subunits of prefoldin, a molecular chaperone complex that binds and stabilizes newly synthesized polypeptides, thereby allowing them to fold correctly. The complex, consisting of two alpha and four beta subunits, forms a double beta barrel assembly with six protruding coiled-coils.[7]

References

Further reading

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