PHF16

Protein Jade-3 is a protein that in humans is encoded by the PHF16 gene.^[5][6]

AliasesJADE3, JADE-3, PHF16, jade family PHD finger 3

External IDsOMIM: 300618; MGI: 2148019; HomoloGene: 40981; GeneCards: JADE3; OMA:JADE3 - orthologs

Chr.X chromosome (human)^[1]

End47,061,242 bp^[1]

Quick facts JADE3, Identifiers ...

JADE3
Identifiers
Aliases	JADE3, JADE-3, PHF16, jade family PHD finger 3
External IDs	OMIM: 300618; MGI: 2148019; HomoloGene: 40981; GeneCards: JADE3; OMA:JADE3 - orthologs
Gene location (Human) Chr. X chromosome (human)[1] Band Xp11.3 Start 46,912,276 bp[1] End 47,061,242 bp[1]
Gene location (Mouse) Chr. X chromosome (mouse)[2] Band X|X A1.3 Start 20,291,927 bp[2] End 20,386,178 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in corpus epididymis caput epididymis placenta right adrenal cortex seminal vesicula ganglionic eminence secondary oocyte left adrenal gland left adrenal cortex gonad Top expressed in tail of embryo superior cervical ganglion genital tubercle yolk sac medullary collecting duct cumulus cell primitive streak ovary islet of Langerhans urothelium More reference expression data BioGPS More reference expression data
Gene ontology Molecular function protein binding metal ion binding Cellular component histone acetyltransferase complex Biological process histone H4-K16 acetylation histone H4-K8 acetylation histone H4-K12 acetylation histone H3 acetylation histone H4-K5 acetylation Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 9767 382207 Ensembl ENSG00000102221 ENSMUSG00000037315 UniProt Q92613 Q6IE82 RefSeq (mRNA) NM_014735 NM_001077445 NM_001289684 NM_199317 RefSeq (protein) NP_001070913 NP_055550 NP_001276613 NP_955021 NP_001393168 NP_001393169 NP_001393170 Location (UCSC) Chr X: 46.91 – 47.06 Mb Chr X: 20.29 – 20.39 Mb PubMed search [3] [4]
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This gene is part of a gene cluster on chromosome Xp11.23. The encoded protein contains a zinc finger motif often found in transcriptional regulators, however, its exact function is not known. Alternative splicing results in multiple transcript variants encoding the same protein.^[6]