PHLPPL

PHLPP2
Identifiers
Aliases	PHLPP2, PHLPPL, PPM3B, PH domain and leucine rich repeat protein phosphatase 2
External IDs	OMIM: 611066; MGI: 2444928; HomoloGene: 71015; GeneCards: PHLPP2; OMA:PHLPP2 - orthologs
Gene location (Human)
Chr.	Chromosome 16 (human)
End	71,724,701 bp
Gene location (Mouse)
Chr.	Chromosome 8 (mouse)
End	110,671,303 bp
RNA expression pattern
	Top expressed in
	mucosa of ileum; ; jejunal mucosa; ; mucosa of colon; ; mucosa of sigmoid colon; ; middle temporal gyrus; ; retinal pigment epithelium; ; germinal epithelium; ; Brodmann area 46; ; duodenum; ; mucosa of transverse colon;
	Top expressed in
	retinal pigment epithelium; ; left colon; ; neural layer of retina; ; dorsomedial hypothalamic nucleus; ; jejunum; ; hand; ; ciliary body; ; substantia nigra; ; paraventricular nucleus of hypothalamus; ; ventral tegmental area;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	catalytic activity; phosphoprotein phosphatase activity; hydrolase activity; metal ion binding; protein binding; protein serine/threonine phosphatase activity;
Cellular component	cytoplasm; cytosol; membrane; nucleus; photoreceptor inner segment; photoreceptor outer segment membrane;
Biological process	hippocampus development; protein dephosphorylation; signal transduction; negative regulation of protein kinase B signaling;
	Sources:Amigo / QuickGO
Orthologs
	23035
	244650
	ENSG00000040199
	ENSMUSG00000031732
	Q6ZVD8
	Q8BXA7
	NM_015020; NM_001289003
	NM_001122594
	NP_001275932; NP_055835
	NP_001116066
	Wikidata
View/Edit Human	View/Edit Mouse

PH domain and leucine rich repeat protein phosphatase-like, also known as PHLPPL, is an enzyme which in humans is encoded by the PHLPPL gene.^[5]