PIK3C3

PIK3C3
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3IHY, 3LS8, 4OYS, 4PH4, 4UWF, 4UWG, 4UWH, 4UWL, 5ANL
Identifiers
Aliases	PIK3C3, VPS34, hVps34, phosphatidylinositol 3-kinase catalytic subunit type 3
External IDs	OMIM: 602609; MGI: 2445019; HomoloGene: 1986; GeneCards: PIK3C3; OMA:PIK3C3 - orthologs
Gene location (Human)
Chr.	Chromosome 18 (human)
End	42,087,830 bp
Gene location (Mouse)
Chr.	Chromosome 18 (mouse)
End	30,481,179 bp
RNA expression pattern
	Top expressed in
	Achilles tendon; ; ventricular zone; ; endothelial cell; ; stromal cell of endometrium; ; ganglionic eminence; ; testicle; ; gonad; ; right adrenal cortex; ; right testis; ; left testis;
	Top expressed in
	lesser wing of sphenoid bone; ; occiput; ; occipital bone; ; Meckel's cartilage; ; rib; ; parotid gland; ; epithelium of stomach; ; submandibular gland; ; granulocyte; ; Gonadal ridge;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	transferase activity; protein kinase activity; nucleotide binding; 1-phosphatidylinositol-3-kinase activity; protein binding; phosphatidylinositol 3-kinase activity; ATP binding; kinase activity;
Cellular component	cytosol; endosome; late endosome; phagocytic vesicle membrane; membrane; phosphatidylinositol 3-kinase complex, class III; autophagosome; midbody; phagocytic vesicle; axoneme; cytoplasmic vesicle; autolysosome; phagophore assembly site; peroxisome; phosphatidylinositol 3-kinase complex, class III, type I; phosphatidylinositol 3-kinase complex, class III, type II; cytoplasm; intracellular anatomical structure;
Biological process	cellular response to glucose starvation; regulation of cytokinesis; phosphorylation; protein processing; response to leucine; cytokinesis; endosome organization; cell division; phosphatidylinositol-3-phosphate biosynthetic process; phosphatidylinositol phosphate biosynthetic process; early endosome to late endosome transport; phosphatidylinositol biosynthetic process; cell cycle; toll-like receptor 9 signaling pathway; macroautophagy; regulation of protein secretion; protein localization to phagophore assembly site; cellular response to starvation; protein lipidation; autophagy; autophagosome assembly; protein phosphorylation; endocytosis; autophagy of peroxisome; phosphatidylinositol-mediated signaling; interleukin-7-mediated signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	5289
	225326
	ENSG00000078142
	ENSMUSG00000033628
	Q8NEB9
	Q6PF93
	NM_001308020; NM_002647
	NM_181414
	NP_001294949; NP_002638
	NP_852079
	Wikidata
View/Edit Human	View/Edit Mouse

Phosphatidylinositol 3-kinase catalytic subunit type 3 is an enzyme subunit that in humans is encoded by the PIK3C3 gene.^[5]^[6] It's a class III phosphoinositide 3-kinase.