PITPNB

Phosphatidylinositol transfer protein beta isoform is a protein that in humans is encoded by the PITPNB gene.^[5][6]

AliasesPITPNB, PI-TP-beta, PtdInsTP, VIB1B, phosphatidylinositol transfer protein beta

External IDsOMIM: 606876; MGI: 1927542; HomoloGene: 4533; GeneCards: PITPNB; OMA:PITPNB - orthologs

Chr.Chromosome 22 (human)^[1]

End27,920,134 bp^[1]

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PITPNB
Identifiers
Aliases	PITPNB, PI-TP-beta, PtdInsTP, VIB1B, phosphatidylinositol transfer protein beta
External IDs	OMIM: 606876; MGI: 1927542; HomoloGene: 4533; GeneCards: PITPNB; OMA:PITPNB - orthologs
Gene location (Human) Chr. Chromosome 22 (human)[1] Band 22q12.1 Start 27,851,669 bp[1] End 27,920,134 bp[1]
Gene location (Mouse) Chr. Chromosome 5 (mouse)[2] Band 5|5 F Start 111,478,629 bp[2] End 111,536,225 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in gingival epithelium secondary oocyte endothelial cell middle temporal gyrus germinal epithelium Brodmann area 23 superficial temporal artery hair follicle cartilage tissue parietal pleura Top expressed in condyle fossa ciliary body hair follicle retinal pigment epithelium endothelial cell of lymphatic vessel vestibular membrane of cochlear duct conjunctival fornix internal carotid artery iris More reference expression data BioGPS More reference expression data
Gene ontology Molecular function lipid binding phosphatidylcholine transporter activity phosphatidylinositol transfer activity phosphatidylcholine binding phosphatidylinositol binding phospholipid transporter activity Cellular component cytoplasm Golgi membrane Golgi apparatus endoplasmic reticulum membrane intracellular anatomical structure Biological process lipid metabolism retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum nucleus organization phospholipid transport Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 23760 56305 Ensembl ENSG00000180957 ENSMUSG00000050017 UniProt P48739 P53811 RefSeq (mRNA) NM_001284277 NM_001284278 NM_012399 NM_001301643 NM_001301644 NM_001301666 NM_019640 NM_001359215 NM_001359216 NM_001359217 RefSeq (protein) NP_001271206 NP_001271207 NP_036531 NP_001288572 NP_001288573 NP_001288595 NP_062614 NP_001346144 NP_001346145 NP_001346146 Location (UCSC) Chr 22: 27.85 – 27.92 Mb Chr 5: 111.48 – 111.54 Mb PubMed search [3] [4]
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The protein encoded by this gene is found in the cytoplasm, where it catalyzes the transfer of phosphatidylinositol and phosphatidylcholine between membranes.^[6]