Plakophilin-3

Protein-coding gene in the species Homo sapiens From Wikipedia, the free encyclopedia

Plakophilin-3 is a protein that in humans is encoded by the PKP3 gene.[5][6]

Quick facts PKP3, Identifiers ...
PKP3
Identifiers
AliasesPKP3, plakophilin 3
External IDsOMIM: 605561; MGI: 1891830; HomoloGene: 5200; GeneCards: PKP3; OMA:PKP3 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_007183
NM_001303029

NM_001162924
NM_019762

RefSeq (protein)

NP_001289958
NP_009114

NP_001156396
NP_062736

Location (UCSC)Chr 11: 0.39 – 0.4 MbChr 7: 140.66 – 140.67 Mb
PubMed search[3][4]
Wikidata
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Function

This gene encodes a member of the arm-repeat (armadillo) and plakophilin gene families. Plakophilin proteins contain numerous armadillo repeats, localize to cell desmosomes and nuclei, and participate in linking cadherins to intermediate filaments in the cytoskeleton. This protein may act in cellular desmosome-dependent adhesion and signaling pathways.[6]

Interactions

PKP3 has been shown to interact with:

References

Further reading

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