PLAG1

Protein-coding gene in the species Homo sapiens From Wikipedia, the free encyclopedia

Zinc finger protein PLAG1 is a protein that in humans is encoded by the PLAG1 gene.[5][6]

AliasesPLAG1, PSA, SGPA, ZNF912, PLAG1 zinc finger, SRS4
End56,211,324 bp[1]
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PLAG1
Identifiers
AliasesPLAG1, PSA, SGPA, ZNF912, PLAG1 zinc finger, SRS4
External IDsOMIM: 603026; MGI: 1891916; HomoloGene: 1993; GeneCards: PLAG1; OMA:PLAG1 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001114634
NM_001114635
NM_002655

NM_019969

RefSeq (protein)

NP_001108106
NP_001108107
NP_002646

NP_064353

Location (UCSC)Chr 8: 56.16 – 56.21 MbChr 4: 3.9 – 3.94 Mb
PubMed search[3][4]
Wikidata
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Function

Pleomorphic adenoma gene 1 encodes a zinc finger protein with 2 putative nuclear localization signals. PLAG1, which is developmentally regulated, has been shown to be consistently rearranged in pleomorphic adenomas of the salivary glands. PLAG1 is activated by the reciprocal chromosomal translocations involving 8q12 in a subset of salivary gland pleomorphic adenomas.[6]

Interactions

PLAG1 has been shown to interact with Karyopherin alpha 2.[7]

References

Further reading

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