PLEK2

PLEK2
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1X1G
Identifiers
Aliases	PLEK2, pleckstrin 2
External IDs	OMIM: 608007; MGI: 1351466; HomoloGene: 8447; GeneCards: PLEK2; OMA:PLEK2 - orthologs
Gene location (Human)
Chr.	Chromosome 14 (human)
End	67,412,167 bp
Gene location (Mouse)
Chr.	Chromosome 12 (mouse)
End	78,953,738 bp
RNA expression pattern
	Top expressed in
	oocyte; ; secondary oocyte; ; mucosa of transverse colon; ; right adrenal cortex; ; gingival epithelium; ; left adrenal gland; ; left adrenal cortex; ; corpus epididymis; ; rectum; ; jejunal mucosa;
	Top expressed in
	Paneth cell; ; molar; ; fetal liver hematopoietic progenitor cell; ; lumbar spinal ganglion; ; gastric mucosa; ; mucous cell of stomach; ; epithelium of stomach; ; pyloric antrum; ; duodenum; ; lip;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	phosphatidylinositol-3,4-bisphosphate binding; phosphatidylinositol-3,5-bisphosphate binding; phosphatidylinositol-3-phosphate binding;
Cellular component	cytoplasm; plasma membrane; cell projection; lamellipodium membrane; cytoskeleton; membrane;
Biological process	intracellular signal transduction; actin cytoskeleton organization; positive regulation of cell projection organization; actin cytoskeleton reorganization; positive regulation of plasma membrane bounded cell projection assembly;
	Sources:Amigo / QuickGO
Orthologs
	26499
	27260
	ENSG00000100558
	ENSMUSG00000021118
	Q9NYT0
	Q9WV52
	NM_016445
	NM_013738
	NP_057529
	NP_038766
	Wikidata
View/Edit Human	View/Edit Mouse

Pleckstrin-2 is a protein that in humans is encoded by the PLEK2 gene.^[5]^[6]^[7] The PLEK2 gene is located on chromosome 14 in Homo sapiens and is flanked by TMEM229B to its right and ATP6V1D to its left.^[8]