POLR2C
Protein-coding gene in the species Homo sapiens
From Wikipedia, the free encyclopedia
DNA-directed RNA polymerase II subunit RPB3 is an enzyme that in humans is encoded by the POLR2C gene.[5]
AliasesPOLR2C, RPB3, RPB31, hRPB33, hsRPB3, polymerase (RNA) II subunit C, RNA polymerase II subunit C
External IDsOMIM: 180663; MGI: 109299; HomoloGene: 2017; GeneCards: POLR2C; OMA:POLR2C - orthologs
Function
This gene encodes the third largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene contains a cysteine rich region and exists as a heterodimer with another polymerase subunit, POLR2J. These two subunits form a core subassembly unit of the polymerase. A pseudogene has been identified on chromosome 21.[6]
