POU4F3

POU4F3
Identifiers
Aliases	POU4F3, BRN3C, DFNA15, POU class 4 homeobox 3, DFNA42, DFNA52
External IDs	OMIM: 602460; MGI: 102523; HomoloGene: 2023; GeneCards: POU4F3; OMA:POU4F3 - orthologs
Gene location (Human)
Chr.	Chromosome 5 (human)
End	146,341,728 bp
Gene location (Mouse)
Chr.	Chromosome 18 (mouse)
End	42,530,314 bp
RNA expression pattern
	Top expressed in
	smooth muscle tissue; ; tibial arteries; ; islet of Langerhans; ; C1 segment;
	Top expressed in
	lumbar spinal ganglion; ; organ of Corti; ; embryo; ; vestibular sensory epithelium; ; neural layer of retina; ; otolith organ; ; utricle; ; saccule; ; basal plate; ; lip;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	DNA binding; sequence-specific DNA binding; DNA-binding transcription factor activity; DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding; DNA-binding transcription factor activity, RNA polymerase II-specific;
Cellular component	nucleoplasm; nucleus; cytoplasm;
Biological process	regulation of transcription, DNA-templated; hearing; inner ear development; visual perception; transcription by RNA polymerase II; transcription, DNA-templated; cell differentiation; positive regulation of transcription by RNA polymerase II; regulation of transcription by RNA polymerase II; vestibulocochlear nerve development; retinal ganglion cell axon guidance; inner ear morphogenesis; inner ear auditory receptor cell differentiation; axon extension; neuromuscular process controlling balance; neuron apoptotic process; inner ear receptor cell differentiation;
	Sources:Amigo / QuickGO
Orthologs
	5459
	18998
	ENSG00000091010
	ENSMUSG00000024497
	Q15319
	Q63955
	NM_002700
	NM_138945
	NP_002691
	NP_620395
	Wikidata
View/Edit Human	View/Edit Mouse

POU domain, class 4, transcription factor 3 is a protein that in humans is encoded by the POU4F3 gene.^[5]^[6] It's a member of BRN-3 group, also known as POU family class 4.