PPP2R5A

Enzyme found in humans From Wikipedia, the free encyclopedia

Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform is an enzyme that in humans is encoded by the PPP2R5A gene.[5]

AliasesPPP2R5A, B56A, PR61A, protein phosphatase 2 regulatory subunit B'alpha, B56alpha
End212,361,853 bp[1]
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PPP2R5A
Identifiers
AliasesPPP2R5A, B56A, PR61A, protein phosphatase 2 regulatory subunit B'alpha, B56alpha
External IDsOMIM: 601643; MGI: 2388479; HomoloGene: 55961; GeneCards: PPP2R5A; OMA:PPP2R5A - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_006243
NM_001199756

NM_144880

RefSeq (protein)

NP_001186685
NP_006234

NP_659129

Location (UCSC)Chr 1: 212.29 – 212.36 MbChr 1: 191.08 – 191.14 Mb
PubMed search[3][4]
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Function

The product of this gene belongs to the phosphatase 2A regulatory subunit B family. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This gene encodes an alpha isoform of the regulatory subunit B56 subfamily.[6]

Interactions

References

Further reading

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