PRB1

Basic salivary proline-rich protein 1 is a protein that in humans is encoded by the PRB1 gene.^[5][6]

AliasesPRB1, PM, PMF, PMS, PRB1L, PRB1M, proline rich protein BstNI subfamily 1, proline rich protein BstNI subfamily 1 (gene/pseudogene)

External IDsOMIM: 180989; MGI: 1924007; GeneCards: PRB1; OMA:PRB1 - orthologs

Chr.Chromosome 12 (human)^[1]

End11,355,591 bp^[1]

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PRB1
Identifiers
Aliases	PRB1, PM, PMF, PMS, PRB1L, PRB1M, proline rich protein BstNI subfamily 1, proline rich protein BstNI subfamily 1 (gene/pseudogene)
External IDs	OMIM: 180989; MGI: 1924007; GeneCards: PRB1; OMA:PRB1 - orthologs
Gene location (Human) Chr. Chromosome 12 (human)[1] Band 12p13.2 Start 11,351,823 bp[1] End 11,355,591 bp[1]
Gene location (Mouse) Chr. Chromosome 10 (mouse)[2] Band 10|10 A4 Start 32,956,550 bp[2] End 33,352,705 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in olfactory zone of nasal mucosa tonsil bone marrow sural nerve bone marrow cell putamen caudate nucleus nucleus accumbens skin of leg superior frontal gyrus Top expressed in ankle triceps brachii muscle muscle of thigh extraocular muscle temporal muscle sternocleidomastoid muscle interventricular septum vastus lateralis muscle tibialis anterior muscle digastric muscle More reference expression data BioGPS More reference expression data
Gene ontology Molecular function molecular function Cellular component extracellular region Biological process biological process Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 5542 76757 Ensembl ENSG00000251655 ENSMUSG00000019787 UniProt P04280 E9Q9K5 RefSeq (mRNA) NM_199354 NM_005039 NM_199353 NM_001367912 NM_029726 NM_001364696 NM_001364697 RefSeq (protein) NP_005030 NP_001354841 NP_084002 NP_001351625 NP_001351626 Location (UCSC) Chr 12: 11.35 – 11.36 Mb Chr 10: 32.96 – 33.35 Mb PubMed search [3] [4]
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The protein encoded by this gene is a proline-rich salivary protein. This gene and five other genes that also encode salivary proline-rich proteins (PRPs), as well as a gene encoding a lacrimal gland PRP, form a PRP gene cluster in the chromosomal 12p13 region. Alternatively spliced transcript variants encoding distinct isoforms have been described.^[6]