PSAPL1

Proactivator polypeptide-like 1 is a protein in humans that is encoded by the PSAPL1 gene. It is a member of the saposin family of proteins. ^[5]

AliasesPSAPL1, prosaposin-like 1 (gene/pseudogene), prosaposin like 1 (gene/pseudogene), prosaposin like 1

External IDsMGI: 1924193; HomoloGene: 105928; GeneCards: PSAPL1; OMA:PSAPL1 - orthologs

Chr.Chromosome 4 (human)^[1]

End7,434,930 bp^[1]

Quick facts Identifiers, Aliases ...

PSAPL1
Identifiers
Aliases	PSAPL1, prosaposin-like 1 (gene/pseudogene), prosaposin like 1 (gene/pseudogene), prosaposin like 1
External IDs	MGI: 1924193; HomoloGene: 105928; GeneCards: PSAPL1; OMA:PSAPL1 - orthologs
Gene location (Human) Chr. Chromosome 4 (human)[1] Band 4p16.1 Start 7,430,285 bp[1] End 7,434,930 bp[1]
Gene location (Mouse) Chr. Chromosome 5 (mouse)[2] Band 5|5 B3 Start 36,361,365 bp[2] End 36,363,912 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in skin of thigh skin of abdomen vulva nipple skin of hip human penis lower lobe of lung body of stomach pharynx right testis Top expressed in skin of external ear pyloric antrum epithelium of stomach lip skin of back esophagus conjunctival fornix superior surface of tongue condyle mucous cell of stomach More reference expression data BioGPS n/a
Gene ontology Molecular function enzyme activator activity G protein-coupled receptor binding Cellular component extracellular region lysosome extracellular space cytoplasm cytosol Biological process regulation of lipid metabolic process prostate gland growth adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway epithelial cell differentiation involved in prostate gland development sphingolipid metabolic process lipid metabolism positive regulation of catalytic activity Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 768239 76943 Ensembl ENSG00000178597 ENSMUSG00000043430 UniProt Q6NUJ1 Q8C1C1 RefSeq (mRNA) NM_001085382 NM_175249 RefSeq (protein) NP_001078851 NP_780458 Location (UCSC) Chr 4: 7.43 – 7.43 Mb Chr 5: 36.36 – 36.36 Mb PubMed search [3] [4]
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