PTPRCAP

Protein tyrosine phosphatase receptor type C-associated protein is an enzyme that in humans is encoded by the PTPRCAP gene.^[5]

AliasesPTPRCAP, CD45-AP, LPAP, protein tyrosine phosphatase, receptor type C associated protein, protein tyrosine phosphatase receptor type C associated protein

External IDsOMIM: 601577; MGI: 97811; HomoloGene: 48358; GeneCards: PTPRCAP; OMA:PTPRCAP - orthologs

Chr.Chromosome 11 (human)^[1]

End67,437,682 bp^[1]

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PTPRCAP
Identifiers
Aliases	PTPRCAP, CD45-AP, LPAP, protein tyrosine phosphatase, receptor type C associated protein, protein tyrosine phosphatase receptor type C associated protein
External IDs	OMIM: 601577; MGI: 97811; HomoloGene: 48358; GeneCards: PTPRCAP; OMA:PTPRCAP - orthologs
Gene location (Human) Chr. Chromosome 11 (human)[1] Band 11q13.2 Start 67,435,510 bp[1] End 67,437,682 bp[1]
Gene location (Mouse) Chr. Chromosome 19 (mouse)[2] Band 19 A|19 3.86 cM Start 4,203,603 bp[2] End 4,206,750 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in granulocyte spleen blood lymph node appendix mucosa of transverse colon bone marrow cell gonad right uterine tube duodenum Top expressed in thymus spleen bone marrow granulocyte jejunum ileum colon pharynx lung morula More reference expression data BioGPS n/a
Orthologs Species Human Mouse Entrez 5790 19265 Ensembl ENSG00000213402 ENSMUSG00000045826 UniProt Q14761 Q64697 RefSeq (mRNA) NM_005608 NM_016933 RefSeq (protein) NP_005599 NP_058629 Location (UCSC) Chr 11: 67.44 – 67.44 Mb Chr 19: 4.2 – 4.21 Mb PubMed search [3] [4]
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The protein encoded by this gene was identified as a transmembrane phosphoprotein specifically associated with tyrosine phosphatase PTPRC/CD45, a key regulator of T- and B-lymphocyte activation. The interaction with PTPRC may be required for the stable expression of this protein.^[5]