Picotamide

Picotamide
Clinical data
AHFS/Drugs.com	International Drug Names
ATC code	B01AC03 (WHO) ;
Identifiers
	IUPAC name 4-methoxy-N,N'-bis(pyridin-3-ylmethyl)isophthalamide;
CAS Number	32828-81-2 ; 80530-63-8 (monohydrate);
PubChem CID	4814;
ChemSpider	4649 ;
UNII	654G2VCI4Q;
CompTox Dashboard (EPA)	DTXSID40186498 ;
ECHA InfoCard	100.046.572
Chemical and physical data
Formula	C21H20N4O3
Molar mass	376.416 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES O=C(NCc1cccnc1)c3cc(C(=O)NCc2cccnc2)c(OC)cc3;
	InChI InChI=1S/C21H20N4O3/c1-28-19-7-6-17(20(26)24-13-15-4-2-8-22-11-15)10-18(19)21(27)25-14-16-5-3-9-23-12-16/h2-12H,13-14H2,1H3,(H,24,26)(H,25,27) ; Key:KYWCWBXGRWWINE-UHFFFAOYSA-N ;
	(verify)

Picotamide is a platelet aggregation inhibitor. It works as a thromboxane synthase inhibitor and a thromboxane receptor inhibitor, the latter by modifying cellular responses to activation of the thromboxane receptor.^[1] Picotamide is licensed in Italy for the treatment of clinical arterial thrombosis and peripheral artery disease.^[2]

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