Pinoxepin

Pinoxepin (INNTooltip International Nonproprietary Name; developmental code name P-5227; pinoxepin hydrochloride (USANTooltip United States Adopted Name)) is an antipsychotic of the tricyclic group with a dibenzoxepin ring system which was developed in the 1960s but was never marketed.^{[1][2][3][4][5]} It was found in clinical trials to have effectiveness in the treatment of schizophrenia similar to that of chlorpromazine and thioridazine.^[4] The drug has marked sedative effects but causes relatively mild extrapyramidal symptoms.^[2][4]

Other namesPinoxepine; P-5227

Routes of
administrationOral

CAS Number

• 14008-66-3
  14008-46-9 (hydrochloride)

PubChem CID

• 6436541

Quick facts Clinical data, Other names ...

Pinoxepin

Clinical data
Other names	Pinoxepine; P-5227
Routes of administration	Oral
Identifiers
IUPAC name 2-[4-[(3Z)-3-(2-Chloro-6H-benzo[c][1]benzoxepin-11-ylidene)propyl]piperazin-1-yl]ethanol
CAS Number	14008-66-3 14008-46-9 (hydrochloride)
PubChem CID	6436541
ChemSpider	4941168
UNII	Y3YKO9X8N8
ChEMBL	ChEMBL2110968
CompTox Dashboard (EPA)	DTXSID301136544
Chemical and physical data
Formula	C23H27ClN2O2
Molar mass	398.93 g·mol−1
3D model (JSmol)	Interactive image
SMILES C1CN(CCN1CC/C=C\2/C3=CC=CC=C3COC4=C2C=C(C=C4)Cl)CCO
InChI InChI=1S/C23H27ClN2O2/c24-19-7-8-23-22(16-19)21(20-5-2-1-4-18(20)17-28-23)6-3-9-25-10-12-26(13-11-25)14-15-27/h1-2,4-8,16,27H,3,9-15,17H2/b21-6- Key:RAAHIUIRJUOMAU-MPUCSWFWSA-N

Close